Q: What is the breakdown of B vitamins per serving?
A: In each serving size (15 drops), there are 2mg Vitamin B3 (Niacinamide); 2mg Vitamin B6 (Pyridoxine); 2.5mg B7 (Biotin); 400mcg B9 (Folate); 1500mcg B12 (Methylcobalamin).
Q: Why did you change the formula from Niacin to Niacinamide?
A: With the original B-Complex formula, many customers were experiencing Niacin flush, a flushing and itching of the skin, generally around the face and neck. We opted to switch from Niacin to Niacinamide to mitigate any customer reactions to the Niacin. Though Niacin flush is ultimately harmless, it can be a disconcerting experience, and we want our customers to have a great experience with our products.
The original formula contained 20mg Niacin; it now contains 2mg Niacinamide.
Both Niacin and Niacinamide are naturally found in foods and in the body, and niacinamide is derived from niacin. Niacin and Niacinamide are both classified as Vitamin B3, though their composition is slightly different. Niacinamide benefits B3 deficiencies just like niacin does, though it doesn't have the same lowering effect on high cholesterol as Niacin. While they differ, Niacinamide is a great non-flushing alternative and is used industry wide.
Please consult your physician if you are interested in supplementing with Niacin for the purpose of treating high cholesterol. They can advise you on dosage and how to diminish the effects of Niacin flush.
Q: Why Methylcobalamin rather than other forms of B12?
A: Methylcobalamin is the most bioavailable form of B12, meaning it will be more readily absorbed into your body. It is also suitable for those who carry the MTHFR gene mutation.
Q: What is the best time of day to take the B-Complex?
A: B vitamins are best absorbed on an empty stomach and tend to give an energy boost, so morning time is the ideal time to take the B-Complex Drops. If you have a sensitive stomach, you may find it better to take the B-Complex with food. You can also split your dosage and take some in the early afternoon, for a boost of energy during the second half of the day!
Q: I noticed that the daily value percentage of the recommended serving size was well over 100% for B7 and B12. Will that be bad for me?!
A: No! Interestingly, the body cannot store water-soluble B vitamins. As such, they have to be regularly replenished. The body excretes excess amounts of water-soluble vitamins through urine, and very rarely reach toxic levels in the body. If you are concerned about dosage, consult your physician or healthcare professional for further information; they will be able to advise the correct dosage for your body’s needs.
Q: I have MTHFR gene variant(s). Is this product safe for me?
A: Navigating B-vitamins and MTHFR can be tricky! While there is a considerable amount of information coming out on genetic variations and how they affect our biochemistry and health, the MTHFR deficiency is not yet fully understood, including how various B-vitamins affect any given individual. Elevated homocysteine levels, often caused by the MTHFR gene variants, is associated with deficiencies in B9 (Folate), B6 and B12.
The primary concern for those with MTHFR gene variant(s) is Folate (vitamin B9). People with MTHFR gene variant(s) need to avoid synthetic forms of folate (B9), like Folic Acid. There seems to be some evidence that Folinic Acid is safe for those with the less severe MTHFR gene variants, while preliminary studies show that those with more severe MTHFR variants may require 5-MTHR (Methylated Folate) supplementation and/or treatment with betaine (trimethylglycine) to aid in metabolizing homocysteine.
We have six products in our line of supplements that contain some form of folate: all three of our Morning Multivitamins, our Kid’s Multivitamin Gummies, Biotin Gummies and our B-Complex Spray.
Of those products, the Liquid Multivitamins Essentials+ (Fruit Punch and Strawberry) & Organic B-Complex have Folinic Acid since methylated folate is not stable in liquid formulas. Folinic Acid is suitable for many with MTHFR. If you are unsure whether or not you can use Calcium Folinate or Folinic Acid, please speak with your physician.
We advise those with the MTHFR gene variants against using the Liquid Morning Multivitamin in Raspberry flavor, as this version currently has non-methylated folate which is not suitable for this with MTHFR. We do plan on updating this formula to have Folinic Acid with the next batch going to production very soon. However, this new formula is not yet available. (If you are interested in this product, please check with us before ordering to ensure the batches have been updated.)
Our Children's Multivitamin Gummies, as well as our Biotin Gummies, contain Methylated Folate (as Calcium L-5-methyl-THF). Methylated folate is considered safest for those with MTHFR, especially for people who have multiple MTHFR variants.
The remaining products in our line of supplements do not have B9. However, we do have a number of products which contain other B-vitamins. We created a spreadsheet to help our customers review all our products with B-vitamins and their forms, so you can make the best choices for your health. Please reach out to our customer care team for access to this spreadsheet. Generally, the vitamer of B6 that is recommended for those with MTHFR variants is Pyridoxal-5-Phosphate (P5P) and the vitamer of B12 that is recommended for those with MTHFR variants is Methylcobalamin. Please consult with your healthcare professional to determine what is best for you.
In general, when starting any new health and wellness supplement, you should check with your physician or healthcare professional to make sure the supplement is suitable for you and your health. This is especially true when there is the added complexity of the MTHFR gene variants. We encourage you to partner with your healthcare professional to determine the best course of action.
Please do not hesitate to let us know of any additional questions you may have or if you need further assistance.